Chemical name : diarsenic trioxide, arsenic trioxide CAS No : 1327-53-3 Product code : LC11505 Formula : As2O3 Synonyms : Arsenous acid / Arseni c (III) oxide / Diarsenic trioxide 1.2. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : For laboratory and manufacturing use only.

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Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide. Arsenic trioxide is approved to be used with tretinoin to treat: Acute promyelocytic leukemia (APL) in patients whose cancer has a certain type of chromosome mutation that affects the PML gene and RARA gene. 2021-01-26 · Some cancer specialists use arsenic trioxide to treat multiple myeloma or cancer found in the bone marrow plasma cells. Other specialists use it to treat other cancers of the bone marrow and blood, such as acute myelogenous leukemia and chronic myelogenous leukemia. Arsenic trioxide uses caspase-dependent and caspase-independent death pathways in myeloma cells.

Arsenic trioxide uses

What Arsenic Trioxide Is Used For: Acute promyelocytic leukemia (APL) Note: If a drug has been approved for one use, physicians sometimes elect to use this same drug for other problems if they believe it may be helpful. How Arsenic Trioxide Is Given: Arsenic trioxide is administered via an intravenous (IV) injection over the course of one or two hours. Arsenic trioxide (Trisenox, ATO) Arsenic trioxide is a chemotherapy drug and is also called Trisenox or ATO. It is a treatment for a type of acute myeloid leukaemia called acute promyelocytic leukaemia (APL). Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. As an industrial chemical major uses include in the manufacture of wood preservatives, pesticides, and glass. As a medication it is used to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein.

Arsenic trioxide is the most important commercial compound of arsenic, and the 2 Chemical properties; 3 Molecular structure; 4 Uses; 5 Medical applications

arsenic trioxide in the EU The uses of As are documented for the glass industry, in wood preservation, in photochemical devices and many other applications. Copyrighted free use Kinetics and mechanism of arsenic sulfides oxidation The synthesis of tungsten trioxide gel by dissolution of tungsten in hydrogen Protopic can be used for short term and intermittent long term treatment. chemotherapy with or without arsenic trioxide (As2O3) as initial consolidation therapy The ion microprobe technique requires the use of standards of the same two facilities continue with the production of arsenic trioxide in the EU The uses of As far more commonly used frontier production function (Ali and Flinn 1989).

'Introduction: The History of Arsenic Trioxide in Cancer Therapy', The Apseloff G 1999, 'Therapeutic Uses of Gallium Nitrate: Past, Present,

Background: Arsenic trioxide delivers high rates of complete clinical remission in patients with relapsed/refractory acute promyelocytic leukaemia (APL), and is associated with high rates of molecular remission as indicated by PCR negativity for the PML-RARalpha gene. Arsenic trioxide uses caspase-dependent and caspase-independent death pathways in myeloma cells.

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After a decline in the use of arsenic during the mid‐20th century, reports from China described a high proportion of hematologic responses in patients with acute promyelocytic leukemia (APL) who were treated with arsenic trioxide. Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and relapsed patients with acute promyelocytic leukemia (APL).

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In Traditional Chinese Medicine, arsenous acid or arsenic trioxide paste is often used to treat tooth marrow disease as a devitalizing agent.

[25] The arsenic trioxide can be purified on site or sold to a refinery. [7] China is the world’s leading producer of arsenic (25,000 tons in 2014) followed by Chile (10,000 tons) and Morocco (8,000 tons). Arsenic trioxide (As2O3) has been shown to be even more effective than all-trans retinoid (ATRA) in the treatment of acute promyelocytic leukemia (APL). The combination of induction of apoptosis, induction of differentiation and inhibiting the proliferation, and killing of APL cells could be the main cellular mechanisms of As2O3 in APL treatment.

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However, arsenic acid and arsenic pentoxide are both included in to which the use of wood treated with arsenic in consumer applications (e.g. in fencing and

In Traditional Chinese Medicine, arsenous acid or arsenic trioxide paste is often used to treat tooth marrow disease as a devitalizing agent. Arsenic trioxide was first purified and used in controlled studies in China in the 1970s.Subsequently, randomised clinical trials performed in the United States led to FDA approval of arsenic trioxide in the treatment of patients with relapsed or refractory acute promyelocytic leukaemia. Chemical name : diarsenic trioxide, arsenic trioxide CAS No : 1327-53-3 Product code : LC11505 Formula : As2O3 Synonyms : Arsenous acid / Arseni c (III) oxide / Diarsenic trioxide 1.2. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : For laboratory and manufacturing use only. Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. As an industrial chemical, whose major uses include in the manufacture of wood preservatives, pesticides, and glass. This versatile agent has a predictable and manageable safety profile and avoids many of the severe toxicities associated with conventional chemotherapies.